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Your translated search: tetrahydrofolate = 139 reactions were found.
State Icon Reaction EC-Number Conf. maximal confidence score from EnzymeDetector PW
tetrahydrofolate + NADP+ <=> 7,8-dihydrofolate + NADPH + H+ 1.5.1.3 dihydrofolate reductase
1.5.1.33 pteridine reductase
1.5.1.34 6,7-dihydropteridine reductase
1.5.1.50 dihydromonapterin reductase




BMK
tetrahydrofolate + ATP + formate <=> 10-formyltetrahydrofolate + ADP + phosphate 6.3.4.3 formate---tetrahydrofolate ligase

BMK
5-formimidoyltetrahydrofolate + L-glutamate <=> N-formimino-L-glutamate + tetrahydrofolate 2.1.2.5 glutamate formimidoyltransferase

BMK
tetrahydrofolate + L-glutamate + ATP <=> tetrahydrofolate + ADP + phosphate 6.3.2.17 tetrahydrofolate synthase

BMK
10-formyltetrahydrofolate + H2O <=> tetrahydrofolate + formate + H+ 3.5.1.10 formyltetrahydrofolate deformylase

BMK
10-formyltetrahydrofolate + H2O + NADP+ <=> tetrahydrofolate + CO2 + NADPH + H+ 1.5.1.6 formyltetrahydrofolate dehydrogenase

K
N,N-dimethylglycine + tetrahydrofolate + flavin <=> sarcosine + 5,10-methylenetetrahydrofolate + reduced_flavodoxin 1.5.8.4 dimethylglycine dehydrogenase

K
L-homocysteine + 5-methyltetrahydrofolate <=> L-methionine + tetrahydrofolate 2.1.1.13 methionine synthase
2.1.1.14 5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase


BMK
L-serine + tetrahydrofolate <=> glycine + 5,10-methylenetetrahydrofolate + H2O 2.1.2.1 glycine hydroxymethyltransferase

BMK
tetrahydrofolate + Trimethylsulfonium <=> H+ + Dimethylsulfide + 5-methyltetrahydrofolate 2.1.1.19 trimethylsulfonium---tetrahydrofolate N-methyltransferase

K
5,10-methylenetetrahydrofolate + 2-oxoisovalerate + H2O <=> ketopantoate + tetrahydrofolate 2.1.2.11 3-methyl-2-oxobutanoate hydroxymethyltransferase

BMK
10-formyltetrahydrofolate + beta-glycinamide_ribonucleotide <=> tetrahydrofolate + formylglycinamide_ribonucleotide + H+ 2.1.2.2 phosphoribosylglycinamide formyltransferase

BMK
10-formyltetrahydrofolate + 5-aminoimidazole-4-carboxamide_ribonucleotide <=> tetrahydrofolate + 5-Formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide 2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase

BMK
5-formimidoyltetrahydrofolate + glycine <=> Formiminoglycine + tetrahydrofolate 2.1.2.4 glycine formimidoyltransferase

BMK
5,10-methylenetetrahydrofolate + D-alanine + H2O <=> 2-methyl-DL-serine + tetrahydrofolate 2.1.2.1 glycine hydroxymethyltransferase
2.1.2.7 D-alanine 2-hydroxymethyltransferase


K
dCMP + H2O + 5,10-methylenetetrahydrofolate <=> 2''-deoxy-5-hydroxymethylcytidine_5''-phosphate + tetrahydrofolate 2.1.2.8 deoxycytidylate 5-hydroxymethyltransferase
2.1.2.B2


K
dUMP + 5,10-methylenetetrahydrofolate + NADPH + H+ <=> dTMP + tetrahydrofolate + NADP+ 1.5.1.3 dihydrofolate reductase
2.1.1.148 thymidylate synthase (FAD)


MK
3-(methylthio)propanoate + 5-methyltetrahydrofolate + H+ <=> dimethylsulfoniopropionate + tetrahydrofolate 2.1.1.269 dimethylsulfoniopropionate demethylase

MK
UDP-4-amino-4-deoxy-beta-L-arabinopyranose + 10-formyltetrahydrofolate <=> UDP-4-deoxy-4-formamido-beta-L-arabinopyranose + tetrahydrofolate + H+ 2.1.2.13 UDP-4-amino-4-deoxy-L-arabinose formyltransferase

MK
vanillic_acid + tetrahydrofolate <=> 3,4-dihydroxybenzoate + 5-methyltetrahydrofolate 2.1.1.341 vanillate/3-O-methylgallate O-demethylase

MK
5-methoxygallic_acid + tetrahydrofolate <=> gallic_acid + 5-methyltetrahydrofolate 2.1.1.341 vanillate/3-O-methylgallate O-demethylase

MK
sesamin + tetrahydrofolate <=> (+)-demethylpiperitol + 5,10-methylenetetrahydrofolate 2.1.5.1 sesamin methylene transferase

(+)-demethylpiperitol + tetrahydrofolate <=> (+)-didemethylpinoresinol + 5,10-methylenetetrahydrofolate 2.1.5.1 sesamin methylene transferase

folate + NADPH <=> tetrahydrofolate + NADP+ 1.5.1.3 dihydrofolate reductase
1.5.1.33 pteridine reductase
1.5.1.34 6,7-dihydropteridine reductase



K
folate + NADH <=> tetrahydrofolate + NAD+ 1.5.1.3 dihydrofolate reductase
1.5.1.34 6,7-dihydropteridine reductase


K
5,10-methylenetetrahydrofolate + tRNA_UpsiC + FADH2 <=> tetrahydrofolate + tRNA_TpsiC + FAD 2.1.1.74 methylenetetrahydrofolate---tRNA-(uracil54-C5)-methyltransferase [NAD(P)H-oxidizing]

S-aminomethyldihydrolipoylprotein + tetrahydrofolate <=> dihydrolipoylprotein + 5,10-methylenetetrahydrofolate + NH3 2.1.2.10 aminomethyltransferase

K
formaldehyde + tetrahydrofolate <=> 5,10-methylenetetrahydrofolate + H2O 2.1.2.11 3-methyl-2-oxobutanoate hydroxymethyltransferase

M
5-formyltetrahydrofolate + L-glutamate <=> N-formyl-L-glutamate + tetrahydrofolate + H+ 2.1.2.5 glutamate formimidoyltransferase

K
ATP + tetrahydrofolate + L-glutamate <=> ADP + phosphate + 5,6,7,8-tetrahydropteroyl-Glu2 6.3.2.17 tetrahydrofolate synthase

K
5,10-methylenetetrahydrofolate + tRNA_UpsiC + NADH <=> tetrahydrofolate + tRNA_TpsiC + NAD+ 2.1.1.74 methylenetetrahydrofolate---tRNA-(uracil54-C5)-methyltransferase [NAD(P)H-oxidizing]

7,8-dihydrofolate + NADH + H+ <=> tetrahydrofolate + NAD+ 1.5.1.3 dihydrofolate reductase

K
syringic_acid + tetrahydrofolate <=> 5-methoxygallic_acid + 5-methyltetrahydrofolate 2.1.1
2.1.1.341 vanillate/3-O-methylgallate O-demethylase


MK
glycine + tetrahydrofolate + NAD+ <=> 5,10-methylenetetrahydrofolate + NH3 + CO2 + NADH 1.4.1.f
1.4.4.2 glycine dehydrogenase (aminomethyl-transferring)
1.8.1.4 dihydrolipoyl dehydrogenase
2.1.2.10 aminomethyltransferase




MK
tetrahydrofolate + H2O <=> tetrahydrofolate + L-glutamate 3.4.19.9 folate gamma-glutamyl hydrolase

MK
D-serine + tetrahydrofolate <=> glycine + 5,10-methylenetetrahydrofolate + H2O 2.1.2.1 glycine hydroxymethyltransferase

5-methyltetrahydrofolate + corrinoid + H+ <=> methylcorrinoid_protein + tetrahydrofolate 2.1.1.258 5-methyltetrahydrofolate---corrinoid/iron-sulfur protein Co-methyltransferase

K
serotonin + 5-methyltetrahydrofolate <=> 5-methoxytryptamine + tetrahydrofolate 2.1.1

K
Met-tRNA + 10-formyltetrahydrofolate <=> tetrahydrofolate + N-formylmethionyl-tRNA 2.1.2.9 methionyl-tRNA formyltransferase

K
5''-Phosphoribosylglycinamide + 5,10-methenyltetrahydrofolate + H2O <=> 5''-Phosphoribosyl-N-formylglycinamide + tetrahydrofolate 2.1.2.2 phosphoribosylglycinamide formyltransferase

K
tRNA_containing_2-thiouridine + glycine + 5-formyltetrahydrofolate + reduced_acceptor <=> tRNA_containing_5-carboxymethylaminomethyl-2-thiouridine + tetrahydrofolate + acceptor + H2O not assigned

tetrahydrofolate + acetyl-CoA <=> 5-methyltetrahydrofolate + CoA + CO 2.1.1.258 5-methyltetrahydrofolate---corrinoid/iron-sulfur protein Co-methyltransferase
2.3.1.169 CO-methylating acetyl-CoA synthase


K
5,10-methylenetetrahydrofolate + uracil54_in_tRNA + NADPH + H+ <=> tetrahydrofolate + 5-methyluracil54_in_tRNA + NADP+ 2.1.1.74 methylenetetrahydrofolate---tRNA-(uracil54-C5)-methyltransferase [NAD(P)H-oxidizing]

5,10-methylenetetrahydrofolate + uracil54_in_tRNA + NADH + H+ <=> tetrahydrofolate + 5-methyluracil54_in_tRNA + NAD+ 2.1.1.74 methylenetetrahydrofolate---tRNA-(uracil54-C5)-methyltransferase [NAD(P)H-oxidizing]

N,N-dimethylglycine + tetrahydrofolate + oxidized_electron_transfer_flavoprotein + H+ <=> sarcosine + 5,10-methylenetetrahydrofolate + reduced_flavodoxin 1.5.8.4 dimethylglycine dehydrogenase

M
[glycine-cleavage_complex_H_protein]_N6-aminomethyldihydrolipoyl-L-lysine + tetrahydrofolate <=> [glycine-cleavage_complex_H_protein]_N6-dihydrolipoyl-L-lysine + 5,10-methylenetetrahydrofolate + NH3 2.1.2.10 aminomethyltransferase

M
a_[methyl-Co(III)_corrinoid_Fe-S_protein] + tetrahydrofolate <=> [Co(I)_corrinoid_Fe-S_protein] + 5-methyltetrahydrofolate + H+ 2.1.1.258 5-methyltetrahydrofolate---corrinoid/iron-sulfur protein Co-methyltransferase

M
10-formyltetrahydrofolate + L-methionyl-[initiator_tRNAMet] <=> tetrahydrofolate + N-formyl-L-methionyl-[initiator_tRNAmet] + H+ 2.1.2.9 methionyl-tRNA formyltransferase

N5-hydroxy-L-ornithine + 10-formyltetrahydrofolate <=> N5-formyl-N5-hydroxy-L-ornithine + tetrahydrofolate not assigned

M
CMP + 5,10-methylenetetrahydrofolate + H2O <=> 5-hydroxymethylcytidine_5''-phosphate + tetrahydrofolate 2.1.2

M
dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose + 10-formyltetrahydrofolate <=> dTDP-4-formamido-4,6-dideoxy-alpha-D-glucose + tetrahydrofolate + H+ not assigned

[methyl-Co(III)_glycine_betaine-specific_corrinoid_protein] + tetrahydrofolate <=> 5-methyltetrahydrofolate + [Co(I)_glycine_betaine-specific_corrinoid_protein] + H+ 2.1.1.hi

M
[methyl-Co(III)_proline_betaine-specific_corrinoid_protein] + tetrahydrofolate <=> 5-methyltetrahydrofolate + [Co(I)_proline_betaine-specific_corrinoid_protein] + H+ 2.1.1.M73

M
5-methyltetrahydrofolate + cob(I)alamin-[methionine_synthase] + H+ <=> tetrahydrofolate + methylcob(III)alamin-[methionine_synthase] not assigned

3-(methylthio)propanoate + tetrahydrofolate <=> 3-Mercaptopropionate + 5-methyltetrahydrofolate 2.1.1

M
sarcosine + oxidized_electron_transfer_flavoprotein + tetrahydrofolate + H+ <=> glycine + 5,10-methenyltetrahydrofolate + reduced_flavodoxin 1.5.8

M
dATP + formate + tetrahydrofolate <=> dADP + phosphate + 10-formyltetrahydrofolate 6.3.4.3 formate---tetrahydrofolate ligase

5,10-methylenetetrahydrofolate + dUMP + FADH2 + O2 <=> dTMP + tetrahydrofolate + FAD + H2O2 2.1.1.148 thymidylate synthase (FAD)

5,10-methylentetrahydrofolate + uracil1939_in_23S_rRNA + FADH2 <=> tetrahydrofolate + 5-methyluracil1939_in_23S_rRNA + FAD 2.1.1.B117

5,10-methylenetetrahydrofolate + dUMP + FADH2 <=> dTMP + tetrahydrofolate + FAD 2.1.1.148 thymidylate synthase (FAD)

B
5,10-methylenetetrahydrofolate + uracil54_in_tRNA + FADH2 <=> tetrahydrofolate + 5-methyluracil54_in_tRNA + FAD 2.1.1.74 methylenetetrahydrofolate---tRNA-(uracil54-C5)-methyltransferase [NAD(P)H-oxidizing]

5,10-methylenetetrahydrofolate + tRNA_UpsiC + FADH2 <=> tetrahydrofolate + tRNA_TpsiC + FAD+ 2.1.1.74 methylenetetrahydrofolate---tRNA-(uracil54-C5)-methyltransferase [NAD(P)H-oxidizing]

N10-formyltetrahydropteroylglutamate + 5''-phosphoribosyl-5-formamino-4-imidazole_carboxamide_ribonucleotide <=> tetrahydrofolate + 5''-phosphoribosyl-5-formamido-4-imidazole_carboxamide_ribonucleotide 2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase

N10-formyltetrahydropteroyltriglutamate + 5''-phosphoribosyl-5-formamino-4-imidazole_carboxamide_ribonucleotide <=> tetrahydrofolate + 5''-phosphoribosyl-5-formamido-4-imidazole_carboxamide_ribonucleotide 2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase

N10-formyltetrahydropteroylheptaglutamate + 5''-phosphoribosyl-5-formamino-4-imidazole_carboxamide_ribonucleotide <=> tetrahydrofolate + 5''-phosphoribosyl-5-formamido-4-imidazole_carboxamide_ribonucleotide 2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase

N10-formyltetrahydropteroylhexaglutamate + 5''-phosphoribosyl-5-formamino-4-imidazole_carboxamide_ribonucleotide <=> tetrahydrofolate + 5''-phosphoribosyl-5-formamido-4-imidazole_carboxamide_ribonucleotide 2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase

N10-formyltetrahydropteroylpentaglutamate + 5''-phosphoribosyl-5-formamino-4-imidazole_carboxamide_ribonucleotide <=> tetrahydrofolate + 5''-phosphoribosyl-5-formamido-4-imidazole_carboxamide_ribonucleotide 2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase

N10-formyltetrahydropteroyltetraglutamate + 5''-phosphoribosyl-5-formamino-4-imidazole_carboxamide_ribonucleotide <=> tetrahydrofolate + 5''-phosphoribosyl-5-formamido-4-imidazole_carboxamide_ribonucleotide 2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase

S-aminomethyldihydrolipoylprotein + tetrahydrofolate <=> enzyme_N6-(dihydrolipoyl)lysine + 5,10-methylenetetrahydrofolate + NH3 2.1.2.10 aminomethyltransferase

tetrahydrofolate + 2-methyl-L-serine <=> 5,10-methylenetetrahydrofolate + D-alanine + H2O 2.1.2.7 D-alanine 2-hydroxymethyltransferase

hydroxycobalamin + 5-methyltetrahydrofolate <=> methylcobalamin + tetrahydrofolate 2.1.1.258 5-methyltetrahydrofolate---corrinoid/iron-sulfur protein Co-methyltransferase

2-(dimethylsulfonio)propanoate + tetrahydrofolate <=> 2-(methylsulfanyl)propanoate + 5-methyltetrahydrofolate 2.1.1.269 dimethylsulfoniopropionate demethylase

2-(dimethylsulfonio)propanoate + tetrahydrofolate <=> 3-(methylthio)propanoate + 5-methyltetrahydrofolate 2.1.1.269 dimethylsulfoniopropionate demethylase

tetrahydrofolate + 2''-deoxyuridine_5''-monophosphate <=> 7,8-dihydrofolate + dTMP 2.1.1.45 thymidylate synthase

a_[methyl-Co(III)_corrinoid_Fe-S_protein] + tetrahydrofolate <=> [Co(I)_corrinoid_Fe-S_protein] + 5-methyltetrahydrofolate 2.1.1.258 5-methyltetrahydrofolate---corrinoid/iron-sulfur protein Co-methyltransferase

B
[Co(I)_corrinoid_Fe-S_protein] + 5-methyltetrahydrofolate <=> a_[methyl-Co(III)_corrinoid_Fe-S_protein] + tetrahydrofolate 2.1.1.258 5-methyltetrahydrofolate---corrinoid/iron-sulfur protein Co-methyltransferase

7,8-dihydrofolate + reduced_acetylpyridine_adenine_dinucleotide <=> tetrahydrofolate + 3-acetylpyridine_adenine_dinucleotide 1.5.1.3 dihydrofolate reductase

CH3-tetrahydrofolate + CO + CoA <=> CH3-CO-S-CoA + tetrahydrofolate 2.3.1.169 CO-methylating acetyl-CoA synthase

tetrahydrofolate + deoxyuridine <=> 7,8-dihydrofolate + dTMP 2.1.1.45 thymidylate synthase

anthranilate + tetrahydrofolate + O2 <=> 3-Hydroxyanthranilate + 7,8-dihydrofolate + H2O2 1.14.16.3 anthranilate 3-monooxygenase

2 L-arginine + 3 tetrahydrofolate + 4 O2 <=> 2 L-citrulline + 2 NO + 3 folate + 4 H2O 1.14.14.47 nitric-oxide synthase (flavodoxin)

N-formimidoyl-L-Glu-L-Glu-L-Glu + tetrahydrofolate <=> N-formimidoyl-L-Glu-L-Glu + 5-formimidoyltetrahydrofolate 2.1.2.5 glutamate formimidoyltransferase

(+)-episesamin + tetrahydrofolate <=> 4-[(1S,3aR,4R,6aR)-4-(2H-1,3-benzodioxol-5-yl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]benzene-1,2-diol + 5,10-methylenetetrahydrofolate 2.1.5.1 sesamin methylene transferase

(-)-asarinin + tetrahydrofolate <=> 4-[(1S,3aS,4R,6aS)-4-(2H-1,3-benzodioxol-5-yl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]benzene-1,2-diol + 4,4''-[(1R,3aS,4S,6aS)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]di(benzene-1,2-diol) + 5,10-methylenetetrahydrofolate 2.1.5.1 sesamin methylene transferase

(+)-sesaminol + tetrahydrofolate <=> 4-[(1S,3aR,4S,6aR)-4-(6-hydroxy-2H-1,3-benzodioxol-5-yl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]benzene-1,2-diol + 5-[(1S,3aR,4S,6aR)-4-(3,4-dihydroxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]benzene-1,2,4-triol + 5,10-methylenetetrahydrofolate 2.1.5.1 sesamin methylene transferase

(+)-sesamolin + tetrahydrofolate <=> 4-[(1S,3aR,4R,6aR)-4-[(2H-1,3-benzodioxol-5-yl)oxy]tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]benzene-1,2-diol + 4-[[(1R,3aR,4S,6aR)-4-(2H-1,3-benzodioxol-5-yl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]oxy]benzene-1,2-diol + 4-[(1S,3aR,4R,6aR)-4-(3,4-dihydroxyphenoxy)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]benzene-1,2-diol + 5,10-methylenetetrahydrofolate 2.1.5.1 sesamin methylene transferase

piperine + tetrahydrofolate <=> (2E,4E)-5-(3,4-dihydroxyphenyl)-1-(piperidin-1-yl)penta-2,4-dien-1-one + 5,10-methylenetetrahydrofolate 2.1.5.1 sesamin methylene transferase

tetrahydrofolate + hydroxymethylserine <=> 5,10-methylenetetrahydrofolate + D-serine + H2O 2.1.2.7 D-alanine 2-hydroxymethyltransferase

5,10-methylenetetrahydrofolate + dUMP <=> tetrahydrofolate + dTMP 2.1.1.45 thymidylate synthase

tetrahydrofolate + 2-ethyl-DL-serine <=> 5,10-methylenetetrahydrofolate + D-2-aminobutyrate + H2O 2.1.2.7 D-alanine 2-hydroxymethyltransferase

tetrahydrofolate + (-)-ethylserine <=> 5,10-methylenetetrahydrofolate + D-2-aminobutyrate + H2O 2.1.2.7 D-alanine 2-hydroxymethyltransferase

S-adenosyl-L-methionine + tetrahydrofolate <=> 5-methyltetrahydrofolate + S-adenosyl-L-homocysteine 2.1.1.13 methionine synthase

dATP + tetrahydrofolate + L-glutamate <=> dADP + phosphate + 5,6,7,8-tetrahydropteroyl-Glu2 6.3.2.17 tetrahydrofolate synthase

ITP + tetrahydrofolate + L-glutamate <=> IDP + phosphate + 5,6,7,8-tetrahydropteroyl-Glu2 6.3.2.17 tetrahydrofolate synthase

tetrahydropteroyl-(gamma-glutamyl)n + (n-1)_H2O <=> tetrahydrofolate + (n-1)_L-glutamate 3.4.19.9 folate gamma-glutamyl hydrolase

CTP + tetrahydrofolate + L-glutamate <=> CDP + phosphate + 5,6,7,8-tetrahydropteroyl-Glu2 6.3.2.17 tetrahydrofolate synthase

UTP + tetrahydrofolate + L-glutamate <=> UDP + phosphate + 5,6,7,8-tetrahydropteroyl-Glu2 6.3.2.17 tetrahydrofolate synthase

10-formyltetrahydrofolate + carbocyclic_beta-glycinamide_ribonucleotide <=> tetrahydrofolate + formylglycinamide_ribonucleotide 2.1.2.2 phosphoribosylglycinamide formyltransferase

10-formyltetrahydrofolate + 5''-phosphoribosyl-5-formamino-4-imidazole_carboxamide_ribonucleotide <=> tetrahydrofolate + 5''-phosphoribosyl-5-formamido-4-imidazole_carboxamide_ribonucleotide 2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase

10-formyltetrahydrofolate + L-methionyl-tRNAfMet <=> tetrahydrofolate + tRNAfMet 2.1.2.9 methionyl-tRNA formyltransferase

10-formyltetrahydrofolate + phenylalanyl-tRNAfMet + H2O <=> tetrahydrofolate + N-formylphenylalanyl-tRNAfMet 2.1.2.9 methionyl-tRNA formyltransferase

10-formyltetrahydrofolate + valyl-tRNAfMet + H2O <=> tetrahydrofolate + N-formylvalyl-tRNAfMet 2.1.2.9 methionyl-tRNA formyltransferase

10-formyltetrahydrofolate + 5-amino-imidazole-4-thiocarboxamide_ribonucleotide <=> tetrahydrofolate + 6-mercaptopurine_ribonucleotide 2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase

10-formyltetrahydrofolate + 5-aminoimidazole-4-carboxamide_ribonucleotide <=> tetrahydrofolate + 5-formamido-4-imidazole_carboxamide_ribonucleotide 2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase

10-formyltetrahydrofolate + isoleucyl-tRNAfMet + H2O <=> tetrahydrofolate + N-formylisoleucyl-tRNAfMet 2.1.2.9 methionyl-tRNA formyltransferase

10-formyltetrahydrofolate + methionyl-tRNA1Val(CAU) + H2O <=> tetrahydrofolate + N-formylmethionyl-tRNA1Val(CAU) 2.1.2.9 methionyl-tRNA formyltransferase

10-formyltetrahydrofolate + methionyl-tRNAmMet + H2O <=> tetrahydrofolate + N-formylmethionyl-tRNAmMet 2.1.2.9 methionyl-tRNA formyltransferase

10-formyltetrahydrofolate + Met-tRNA <=> tetrahydrofolate + N-formylmethionyl-tRNAMet 2.1.2.9 methionyl-tRNA formyltransferase

10-formyltetrahydrofolate + (alpha,beta)-glycinamide_ribonucleotide <=> tetrahydrofolate + formylglycinamide_ribonucleotide 2.1.2.2 phosphoribosylglycinamide formyltransferase

10-formyltetrahydrofolate + O-phosphonate_carbocyclic_glycinamide_ribonucleotide <=> tetrahydrofolate + O-phosphonate-ribosyl-N-formylglycinamide 2.1.2.2 phosphoribosylglycinamide formyltransferase

10-formyltetrahydrofolate + E._coli_L-methionyl-tRNAfMet <=> tetrahydrofolate + tRNAfMet 2.1.2.9 methionyl-tRNA formyltransferase

10-formyltetrahydrofolate + E._coli_L-methionyl-tRNAfMet <=> tetrahydrofolate + E._coli_N-formylmethionyl-tRNAfMet 2.1.2.9 methionyl-tRNA formyltransferase

10-formyltetrahydrofolate + E.coli_L-methionyl-tRNAfMet <=> tetrahydrofolate + E.coli_N-formylmethionyl-tRNAfMet 2.1.2.9 methionyl-tRNA formyltransferase

10-formyltetrahydrofolate + E._coli_L-isoleucyl-tRNAfMet <=> tetrahydrofolate + E._coli_N-formylisoleucyl-tRNAfMet 2.1.2.9 methionyl-tRNA formyltransferase

10-formyltetrahydrofolate + E._coli_L-valyl-tRNAfMet <=> tetrahydrofolate + N-formylvalyl-tRNAfMet 2.1.2.9 methionyl-tRNA formyltransferase

10-formyltetrahydrofolate + E._coli_L-valyl-tRNAfMet <=> tetrahydrofolate + E._coli_N-formylvalyl-tRNAfMet 2.1.2.9 methionyl-tRNA formyltransferase

10-formyltetrahydrofolate + bovine_mitochondrial_L-methionyl-tRNA <=> tetrahydrofolate + bovine_mitochondrial_N-formylmethionyl-tRNA 2.1.2.9 methionyl-tRNA formyltransferase

10-formyltetrahydrofolate + E._coli_L-methionyl-tRNAmMet <=> tetrahydrofolate + N-formylmethionyl-tRNAmMet 2.1.2.9 methionyl-tRNA formyltransferase

10-formyltetrahydrofolate + E._coli_L-methionyl-tRNAmMet <=> tetrahydrofolate + E._coli_N-formylmethionyl-tRNAmMet 2.1.2.9 methionyl-tRNA formyltransferase

10-formyltetrahydrofolate + E._coli_L-methionyl-tRNA1Val(CAU) <=> tetrahydrofolate + E._coli_N-formylisoleucyl-tRNA1Val(CAU) 2.1.2.9 methionyl-tRNA formyltransferase

10-formyltetrahydrofolate + L-isoleucyl-tRNAfMet <=> tetrahydrofolate + N-formylisoleucyl-tRNAfMet 2.1.2.9 methionyl-tRNA formyltransferase

10-formyltetrahydrofolate + L-phenylalanyl-tRNAfMet + H2O <=> tetrahydrofolate + N-formylphenylalanyl-tRNAfMet 2.1.2.9 methionyl-tRNA formyltransferase

10-formyltetrahydrofolate + N5-hydroxy-L-ornithine <=> tetrahydrofolate + N2-formyl-N5-hydroxyornithine 2.1.2.2 phosphoribosylglycinamide formyltransferase

10-formyltetrahydrofolate + N5-hydroxy-L-ornithine <=> tetrahydrofolate + N5-formyl-N5-hydroxyornithine 2.1.2.2 phosphoribosylglycinamide formyltransferase

N10-formyltetrahydropteroylglutamate + 5-aminoimidazole-4-carboxamide_ribonucleotide <=> tetrahydrofolate + 5-formamido-4-imidazole_carboxamide_ribonucleotide 2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase

5,10-methylenetetrahydrofolate + dUMP + FMNH2 <=> dTMP + tetrahydrofolate + FMN 2.1.1.148 thymidylate synthase (FAD)

5-methyltetrahydrofolate + 2-mercaptoethanol <=> S-Methyl-2-mercaptoethanol + tetrahydrofolate 2.1.1.13 methionine synthase

syringic_acid + 2 tetrahydrofolate <=> 3,4-dihydroxybenzoate + 2 5-methyltetrahydrofolate 2.1.1.341 vanillate/3-O-methylgallate O-demethylase

folate + NADPH + H+ <=> 7,8-dihydrofolate + tetrahydrofolate + NADP+ 1.5.1.33 pteridine reductase

5,10-methylenetetrahydrofolate + uracil54_in_tRNA + NADPH + H+ <=> tetrahydrofolate + 5-methyluracil54_in_tRNA + NADP+ 2.1.1.74 methylenetetrahydrofolate---tRNA-(uracil54-C5)-methyltransferase [NAD(P)H-oxidizing]

7,8-dihydrofolate + NADP+ + H+ <=> tetrahydrofolate + NADP+ 1.5.1.3 dihydrofolate reductase

Cobalamin + 5-methyltetrahydrofolate <=> methylcobalamin + tetrahydrofolate 2.1.1.258 5-methyltetrahydrofolate---corrinoid/iron-sulfur protein Co-methyltransferase

ATP + 5,6,7,8-Tetrahydropteroate + L-glutamate <=> ADP + phosphate + tetrahydrofolate 6.3.2.17 tetrahydrofolate synthase

5,10-methenyltetrahydrofolate + 2-amino-N-ribosylacetamide_5''-phosphate + H2O <=> formylglycinamide_ribonucleotide + tetrahydrofolate + 2-formamido-N-ribosylacetamide_5''-phosphate 2.1.2.2 phosphoribosylglycinamide formyltransferase

5-methyltetrahydropteroylmonoglutamate + L-homocysteine <=> tetrahydrofolate + L-methionine 2.1.1.14 5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase

5,10-methylenetetrahydrofolate + H2O + CMP <=> tetrahydrofolate + 5-hydroxymethylcytidylate 2.1.2.B2

5,10-methylenetetrahydrofolate + H2O + CMP <=> tetrahydrofolate + 5-hydroxymethyl-CMP 2.1.2.B2

5,10-methylenetetrahydrofolate + H2O + 2-oxobutyrate <=> 4-Hydroxy-3-methyl-2-oxobutanoic_acid + tetrahydrofolate 2.1.2.11 3-methyl-2-oxobutanoate hydroxymethyltransferase

3-methyl-2-oxopentanoate + H2O + 5,10-methylenetetrahydrofolate <=> 3-(Hydroxymethyl)-3-methyl-2-oxopentanoic_acid + tetrahydrofolate 2.1.2.11 3-methyl-2-oxobutanoate hydroxymethyltransferase